Only the job description changed.
| Previous Job Description | Current Job Description | ||||
|---|---|---|---|---|---|
| n | 1 | Job Description: | n | ||
| 2 | The Cardiovascular Genetics Center at University of California, San Francisco is seeking an experien | 1 | The Cardiovascular Genetics Center at University of California, San Francisco is seeking an experien | ||
| > | ced bioinfomatician to faciliate several lines of research that relate broadly to inherited forms of | > | ced bioinfomatician to faciliate several lines of research that relate broadly to inherited forms of | ||
| > | cardiovascular disease, regulation of gene expression in health and disease, and personalized genet | > | cardiovascular disease, regulation of gene expression in health and disease, and personalized genet | ||
| > | ic medicine. The incumbent will work closely with prinicpal investigators within the Genetic Center | > | ic medicine. The incumbent will work closely with prinicpal investigators within the Genetic Center | ||
| > | to design and implement analysis pipelines in several broad areas of computational biology including | > | to design and implement analysis pipelines in several broad areas of computational biology including | ||
| > | analysis of experimentally generated datasets in basic research, and analysis of patient-derived ge | > | analysis of experimentally generated datasets in basic research, and analysis of patient-derived ge | ||
| > | nomic data from UCSF patients as well as publicly available data repositories. The goal will be to m | > | nomic data from UCSF patients as well as publicly available data repositories. The goal will be to m | ||
| > | ake fundamental biological discoveries that can ultimately be translated to understanding, prevent, | > | ake fundamental biological discoveries that can ultimately be translated to understanding, prevent, | ||
| > | and treat heritable cardiovascular diseases. | > | and treat heritable cardiovascular diseases. | ||
| n | n | 2 | More specifically, the role involves developing and utilizing computational tools and systems to ana | ||
| > | lyze and interpret biological or other research data. Utilizes and develops algorithms, computationa | ||||
| > | l techniques, and statistical methodologies. Helps in the design of new experiments. Implements end- | ||||
| > | user needs in database searching and integration. Maintains the computational infrastructure and tra | ||||
| > | cks the flow of samples and information for large-scale studies. Provides web-based bioinformatics a | ||||
| > | nd access to public and proprietary databases. | ||||
| 3 | 3 | ||||
| t | 4 | Qualifications: | t | 4 | The scope of work will include anayzing biological datasets generated experimentally including but n |
| > | ot limited to bulk and single cell multiomics sequencing, epigenomics data including ChIP-Seq and CU | ||||
| > | T&RUN, and imaging data including spatial transcriptomics; overlapping experimental data with public | ||||
| > | aly available genomic and expression datasets including UK Biobank, All of Us, Heart Cell Atlas, and | ||||
| > | similar datasets. There will also be analysis of genome sequencing data including whole exome- and | ||||
| > | whole genome sequencing to discern rare and common variants implicated in cardiovascular disease.The | ||||
| > | incumbent will also implement machine learning algorithms to analyze biological datasets. There wil | ||||
| > | l be frequent collaboration with bench scientists and clinicians in a highly collegial and stimulati | ||||
| > | ng scientific environment. | ||||
| 5 | Required Qualifications - Bachelor's degree in biological science, computational / programming, or r | ||||
| > | elated area and / or equivalent experience / training - A minimum of 3 years of relevant work experi | ||||
| > | ence in bioinformatics or computational biology - Thorough knowledge of bioinformatics programming d | ||||
| > | esign, modification and implementation in relevant languages such as Python, R, and/or equivalent - | ||||
| > | Understanding of relational databases, web interfaces, and operating systems - Strong project manage | ||||
| > | ment skills - Thorough knowledge of modern biology and applicable field of research - Communication | ||||
| > | skills to work with both technical and non-technical personnel in multiple fields of expertise and a | ||||
| > | t various levels in the organization - Ability to communicate technical information in a clear and c | ||||
| > | oncise manner - Ability to interface with management on a regular basis - Self motivated, work indep | ||||
| > | endently or as part of a team, able to learn quickly, meet deadlines and demonstrate problem solving | ||||
| > | skills - Thorough knowledge of web, application and data security concepts and methods - Familiarit | ||||
| > | y with cloud-based computing and high-performance computing environments - Proven expertise, as refl | ||||
| > | ected in publication record, in analyzing high-throughput sequencing datasets, including RNA-sequenc | ||||
| > | ing, ATAC-sequencing, and chromatin occupancy studies - Thorough In-depth knowledge of genomic datab | ||||
| > | ases, tools, and statistical frameworks Preferred Qualifications - PhD in Bioinformatics or a closel | ||||
| > | y related field | ||||