Only the job description changed.
| Previous Job Description | Current Job Description | ||||
|---|---|---|---|---|---|
| n | 1 | Job Description: | n | 1 | The overall goal of the position is to support the developing research enterprises of the Child Heal |
| > | th Advanced Molecular Phenotyping (CHAMP) Program, which is designed to help investigators better un | ||||
| > | derstand childhood disease by making high-quality human biological samples and molecular data more a | ||||
| > | ccessible across UCSF. | ||||
| 2 | The overall goal of the position is to support the developing research enterprises of the Child Heal | ||||
| > | th Advanced Molecular Phenotyping (CHAMP) Program, which is designed to help investigators better un | ||||
| > | derstand childhood disease by making high-quality human biological samples and molecular data more a | ||||
| > | ccessible across UCSF. Many serious pediatric illnesses remain difficult to explain using traditiona | ||||
| > | l clinical information alone. CHAMP addresses this gap by supporting the careful collection, process | ||||
| > | ing, preservation, and study of biological samples from children across a wide range of diseases and | ||||
| > | clinical settings. The goal is to make it easier for researchers to connect what is happening in a | ||||
| > | child's body at the molecular and cellular level with the clinical course of illness. CHAMP is built | ||||
| > | around two complementary goals. The first is to create a coordinated infrastructure for collecting | ||||
| > | biofluids and tissues from willing participants, especially children with severe, rare, or poorly un | ||||
| > | derstood diseases. Whenever possible, samples are obtained from the sites most relevant to disease a | ||||
| > | nd are processed using protocols designed to preserve their value for both current and future techno | ||||
| > | logies. The second goal is to pair these samples with advanced molecular profiling platforms that ca | ||||
| > | n generate detailed information about immune responses, gene expression, cellular states, antibodies | ||||
| > | , pathogens, and other features of disease biology. These data can then be used by investigators acr | ||||
| > | oss UCSF to generate new hypotheses, identify disease mechanisms, and ultimately improve diagnosis a | ||||
| > | nd treatment for children. CHAMP operates under IRB-approved protocols that allow collection of huma | ||||
| > | n biofluids and tissues, including biopsy and post-mortem specimens, across organ systems and age gr | ||||
| > | oups. The program has developed workflows for rapid processing, cryopreservation, and live cell pres | ||||
| > | ervation so that valuable samples can be studied with the best available technologies. To accomplish | ||||
| > | these goals, CHAMP is primarily based in the Bodansky Lab but works closely and collaboratively wit | ||||
| > | h many additional laboratories across the UCSF ecosystem, and in particular the DeRisi Lab, Anderson | ||||
| > | Lab, Wilson Lab, and Arnold Labs, and applies state of the art technologies to unique patient cohor | ||||
| > | ts towards transformative translational discovery. The Staff Research Associate will be involved in | ||||
| > | the laboratory to support these goals. The primary role will be to process the biological samples ob | ||||
| > | tained and to integrate with the team to optimally store and track them for downstream analysis and | ||||
| > | scientific inquiry. Duties will include a broad range of cell culture, human sample processing, bioc | ||||
| > | hemical, molecular, and functional genomic techniques, as well as learning to apply new technologies | ||||
| > | currently being developed | ||||
| 3 | 2 | ||||
| t | 4 | Qualifications: | t | 3 | Many serious pediatric illnesses remain difficult to explain using traditional clinical information |
| > | alone. CHAMP addresses this gap by supporting the careful collection, processing, preservation, and | ||||
| > | study of biological samples from children across a wide range of diseases and clinical settings. Th | ||||
| > | e goal is to make it easier for researchers to connect what is happening in a child's body at the mo | ||||
| > | lecular and cellular level with the clinical course of illness. | ||||
| 5 | Required Qualifications: - BA/BS in a related science; or an equivalent combination of education and | 4 | |||
| > | experience - Basic understanding of immunology - Computer proficiency, experience with Excel - Expe | ||||
| > | rience working with human biospecimens - Knowledge of basic laboratory techniques: pipetting, prepar | ||||
| > | ation of buffers, serial dilutions, chemical weighing and handling Preferred Qualifications: - Cours | ||||
| > | ework or knowledge of immunology - Working experience with Python and/or R - Familiarity with databa | ||||
| > | se and statistical software - Interest in pediatric translation and basic science | ||||
| 5 | CHAMP is built around two complementary goals. The first is to create a coordinated infrastructure | ||||
| > | for collecting biofluids and tissues from willing participants, especially children with severe, rar | ||||
| > | e, or poorly understood diseases. Whenever possible, samples are obtained from the sites most releva | ||||
| > | nt to disease and are processed using protocols designed to preserve their value for both current an | ||||
| > | d future technologies. | ||||
| 6 | |||||
| 7 | The second goal is to pair these samples with advanced molecular profiling platforms that can gener | ||||
| > | ate detailed information about immune responses, gene expression, cellular states, antibodies, patho | ||||
| > | gens, and other features of disease biology. These data can then be used by investigators across UCS | ||||
| > | F to generate new hypotheses, identify disease mechanisms, and ultimately improve diagnosis and trea | ||||
| > | tment for children. | ||||
| 8 | |||||
| 9 | CHAMP operates under IRB-approved protocols that allow collection of human biofluids and tissues, i | ||||
| > | ncluding biopsy and post-mortem specimens, across organ systems and age groups. The program has deve | ||||
| > | loped workflows for rapid processing, cryopreservation, and live cell preservation so that valuable | ||||
| > | samples can be studied with the best available technologies. | ||||
| 10 | |||||
| 11 | To accomplish these goals, CHAMP is primarily based in the Bodansky Lab but works closely and colla | ||||
| > | boratively with many additional laboratories across the UCSF ecosystem, and in particular the DeRisi | ||||
| > | Lab, Anderson Lab, Wilson Lab, and Arnold Labs, and applies state of the art technologies to unique | ||||
| > | patient cohorts towards transformative translational discovery. | ||||
| 12 | |||||
| 13 | The Staff Research Associate will be involved in the laboratory to support these goals. The primary | ||||
| > | role will be to process the biological samples obtained and to integrate with the team to optimally | ||||
| > | store and track them for downstream analysis and scientific inquiry. Duties will include a broad ra | ||||
| > | nge of cell culture, human sample processing, biochemical, molecular, and functional genomic techniq | ||||
| > | ues, as well as learning to apply new technologies currently being developed | ||||